James M Ntambi Selected Research

Stearoyl-CoA Desaturase

1/2019	Interleukin-6 derived from cutaneous deficiency of stearoyl-CoA desaturase- 1 may mediate metabolic organ crosstalk among skin, adipose tissue and liver.
1/2017	Stearoyl-CoA Desaturase Promotes Liver Fibrosis and Tumor Development in Mice via a Wnt Positive-Signaling Loop by Stabilization of Low-Density Lipoprotein-Receptor-Related Proteins 5 and 6.
12/2015	Microbiota-Dependent Hepatic Lipogenesis Mediated by Stearoyl CoA Desaturase 1 (SCD1) Promotes Metabolic Syndrome in TLR5-Deficient Mice.
10/2015	Saturated phosphatidic acids mediate saturated fatty acid-induced vascular calcification and lipotoxicity.
12/2011	The role of stearoyl-CoA desaturase in obesity, insulin resistance, and inflammation.
1/2011	Stearoyl CoA desaturase 1: role in cellular inflammation and stress.
9/2010	Adipose-specific deletion of stearoyl-CoA desaturase 1 up-regulates the glucose transporter GLUT1 in adipose tissue.
8/2010	Loss of stearoyl-CoA desaturase 1 rescues cardiac function in obese leptin-deficient mice.
6/2010	Genetic control of de novo lipogenesis: role in diet-induced obesity.
2/2009	Stearoyl-CoA desaturase and its relation to high-carbohydrate diets and obesity.

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James M Ntambi Research Topics

Disease

37	Obesity 12/2020 - 02/2003
24	Insulin Resistance 01/2020 - 08/2002
10	Inflammation (Inflammations) 09/2019 - 02/2008
7	Neoplasms (Cancer) 09/2019 - 02/2003
6	Body Weight (Weight, Body) 01/2016 - 02/2004
5	Metabolic Syndrome (Dysmetabolic Syndrome X) 01/2017 - 12/2003
4	Weight Gain 01/2020 - 08/2002
4	Metabolic Diseases (Metabolic Disease) 12/2019 - 10/2015
4	Cardiovascular Diseases (Cardiovascular Disease) 09/2019 - 02/2003
4	Hypercholesterolemia 05/2008 - 05/2005
4	Cholestasis 05/2008 - 12/2006
3	Carcinogenesis 11/2018 - 12/2002
3	Dyslipidemias (Dyslipidemia) 10/2018 - 06/2006
3	Fatty Liver 01/2016 - 02/2004
3	Weight Loss (Weight Reduction) 03/2009 - 07/2002
3	Hypoglycemia (Reactive Hypoglycemia) 05/2008 - 09/2004
2	Prostatic Neoplasms (Prostate Cancer) 01/2019 - 01/2012
2	Type 2 Diabetes Mellitus (MODY) 12/2017 - 10/2005
2	Glucose Intolerance 11/2013 - 05/2007
2	Hyperglycemia 01/2011 - 02/2004
2	Communicable Diseases (Infectious Diseases) 08/2008 - 02/2008
2	Starvation 06/2008 - 12/2003
2	Hyperlipidemias (Hyperlipidemia) 06/2008 - 11/2002
2	Hypertriglyceridemia 09/2006 - 11/2002
2	Hyperinsulinism (Hyperinsulinemia) 07/2006 - 02/2004
2	Atherosclerosis 11/2004 - 12/2002
1	Autoimmune Diseases (Autoimmune Disease) 12/2021
1	Hypothyroidism 12/2020
1	Cardiotoxicity 01/2020
1	Multiple Sclerosis 01/2020
1	Stomach Neoplasms (Stomach Cancer) 01/2020
1	Vitamin D Deficiency 01/2020
1	Liver Diseases (Liver Disease) 09/2019
1	Carcinoma (Carcinomatosis) 01/2019
1	Atrophy 01/2018
1	Dry Eye Syndromes (Dry Eye Syndrome) 01/2018
1	Hyperplasia 01/2018
1	Meibomian Gland Dysfunction 01/2018
1	Tics (Tic) 01/2017
1	Liver Cirrhosis (Hepatic Cirrhosis) 01/2017
1	Alcoholic Fatty Liver 11/2016

Drug/Important Bio-Agent (IBA)

25	Stearoyl-CoA DesaturaseIBA 01/2019 - 06/2002
18	stearoyl-coenzyme A (stearoyl-CoA)IBA 11/2018 - 07/2002
17	LipidsIBA 12/2020 - 03/2005
12	EnzymesIBA 12/2021 - 03/2004
11	LeptinIBA 08/2010 - 07/2002
8	Glucose (Dextrose)FDA LinkGeneric 12/2019 - 09/2004
8	Oleic Acid (Oleate)IBA 11/2018 - 09/2004
7	Monounsaturated Fatty AcidsIBA 12/2021 - 02/2003
7	Triglycerides (Triacylglycerol)IBA 12/2020 - 11/2002
6	CarbohydratesIBA 12/2019 - 12/2006
6	Fatty Acids (Saturated Fatty Acids)IBA 10/2015 - 06/2008
6	Insulin (Novolin)FDA Link 08/2015 - 07/2006
3	DiglyceridesIBA 12/2020 - 11/2012
3	StearatesIBA 01/2019 - 12/2005
3	Proteins (Proteins, Gene)FDA Link 01/2019 - 01/2017
3	Bile Acids and Salts (Bile Acids)IBA 01/2018 - 12/2006
3	Hormones (Hormone)IBA 08/2015 - 12/2003
3	Conjugated Linoleic AcidsIBA 03/2004 - 06/2002
2	Interleukin-6 (Interleukin 6)IBA 01/2019 - 10/2018
2	palmitoleic acidIBA 12/2017 - 01/2010
2	Fatty Acid Synthases (Fatty Acid Synthase)IBA 04/2013 - 06/2010
2	LipopolysaccharidesIBA 01/2010 - 02/2008
2	Lipoprotein-XIBA 01/2007 - 12/2006
2	BilirubinIBA 01/2007 - 12/2006
2	Sterol Regulatory Element Binding Protein 1IBA 07/2006 - 05/2005
2	Phospholipids (Phosphatides)FDA LinkGeneric 03/2004 - 02/2003
1	Inositol (Myoinositol)IBA 12/2021
1	nervonic acidIBA 01/2020
1	dikanutIBA 01/2020
1	Trastuzumab (Herceptin)FDA Link 01/2020
1	Adenosine Triphosphate (ATP)IBA 01/2020
1	Monoclonal AntibodiesIBA 01/2020
1	AntioxidantsIBA 01/2020
1	DNA (Deoxyribonucleic Acid)IBA 01/2020
1	Estrogens (Estrogen)FDA Link 01/2020
1	Free RadicalsIBA 01/2020
1	Immunoglobulin E (IgE)IBA 01/2020
1	NucleotidesIBA 01/2020
1	Vitamin D FDA LinkGeneric 01/2020
1	fibroblast growth factor 21IBA 12/2019
1	Olive OilIBA 09/2019
1	PalmitatesIBA 01/2019
1	Toll-Like Receptor 4IBA 10/2018
1	Serum Amyloid A Protein (Serum Amyloid A)IBA 10/2018
1	lipopolysaccharide-binding proteinIBA 10/2018
1	Methionine (L-Methionine)FDA Link 02/2018
1	Pharmaceutical PreparationsIBA 01/2018
1	MucinsIBA 01/2018
1	Sterol Regulatory Element Binding ProteinsIBA 01/2017
1	CateninsIBA 01/2017
1	NitrosaminesIBA 01/2017
1	LDL Receptors (LDL Receptor)IBA 01/2017
1	Ethanol (Ethyl Alcohol)IBA 11/2016
1	MicroRNAs (MicroRNA)IBA 03/2016
1	Caseins (Casein)FDA Link 01/2016
1	Small Interfering RNA (siRNA)IBA 10/2015

Therapy/Procedure

1	Therapeutics 01/2019
1	Caloric Restriction 01/2017
1	Fat-Restricted Diet (Diet, Fat Restricted) 01/2016